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KMID : 0359920080270020234
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Korean Journal of Nephrology
2008 Volume.27 No. 2 p.234 ~ p.237
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IgA Nephropathy Associated with Chronic Urate Nephropathy
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Cho Jin-Hee
Yu Su-Kyong
Park Jung-Il
Lee Myoung-Hee
Lim Nam-Kyu
Park In-Whee
Kim Heung-Soo
Yim Hyun-Ee
Shin Gyu-Tae
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Abstract
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IgA nephropathy is the most common primary glomerulonephritis and characterized by deposition of IgA in glomerular mesangial area. Chronic urate nephropathy is characterized by precipitation of uric acid crystals in the collecting ducts and medullary interstitium. We report a case of IgA nephropathy associated with chronic urate nephropathy. A 57 year old man underwent percutaneous renal biopsy for gross hematuria, generalized edema and renal failure. Renal biopsy showed typical findings of IgA nephropathy: increased mesangial matrix, cellular proliferation and positive staining of IgA. In addition, crystalline deposits of uric acid, which is typical of chronic urate nephropathy, were seen in the medullary interstitium.
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KEYWORD
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IgA nephropathy, Uric acid, Glomerulonephritis
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